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SEGMENTAL DUPLICATIONS: AN 'EXPANDING' ROLE IN GENOMIC INSTABILITY AND DISEASE

✍ Scribed by Emanuel, Beverly S.; Shaikh, Tamim H.


Book ID
109775899
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
641 KB
Volume
2
Category
Article
ISSN
1471-0056

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## Abstract Multiple myeloma (MM) is a malignant plasma cell disorder characterized by complex karyotypes and chromosome 1 instability at the cytogenetic level. Chromosome 1 instability generally involves partial duplications, whole‐arm translocations, or jumping translocations of 1q, identified by