Seeing Theranostic Nano-Carriers by Freeze-Fracture Electron Microscopy
โ Scribed by Papahadjopoulos-Sternberg, Brigitte
- Book ID
- 122754521
- Publisher
- Biophysical Society
- Year
- 2011
- Tongue
- English
- Weight
- 37 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0006-3495
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The most common electron microscopic technique for obtaining information on size distributions of uncollapsed membrane vesicles is based on the method of van Venetie (1980). This technique involves the sizing of only those vesicles that were freeze fractured at their equatorial planes.
This paper describes the application ofboth SEM and freeze-fracture TEMfor the characterization of artificial lipid vesicles (liposomes). Size and shape may be observed in the SEM technique whereas the inner structure could be investigated best in pictures obtained using the freeze-fracture method.