𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Seeing the light: calcium imaging in cells for drug discovery

✍ Scribed by Larry C Mattheakis; Lynne D Ohler

Book ID
114383235
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
181 KB
Volume
5
Category
Article
ISSN
1359-6446

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## Abstract A major limitation to the clinical usefulness of cancer chemotherapy is the onset of acquired drug resistance, in which the effectiveness of a drug such as Doxorubicin (DOX), used in a wide variety of neoplasms, diminishes following repeated administration. Resistance is associated with