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Secretion of TGFβ by rat alveolar macrophages and characterization of receptors for TGFβ on rat lung fibroblasts

✍ Scribed by Meena, Venkataraman; Macdonald, David W.; Montgomery, Robert A.


Book ID
121765748
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
178 KB
Volume
1
Category
Article
ISSN
1043-4666

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## Abstract The aim of this study was to investigate whether transforming growth factor-β1 (TGF-β1) could induce alveolar epithelial-mesenchymal transition (EMT) in vitro, and whether Smad7 gene transfer could block this transition. We also aimed to elucidate the possible mechanisms of these proces