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Evidence for the involvement of TGF-β and PDGF in the regulation of prolyl 4-hydroxylase and lysyloxidase in cultured rat lung fibroblasts

✍ Scribed by Roland Koslowski; Dagmar Seidel; Eberhard Kuhlisch; Klaus-Peter Knoch

Book ID
114493907
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
177 KB
Volume
55
Category
Article
ISSN
0940-2993

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## Abstract The concerted action of TGF‐β and PDGF on a diploid human embryonic lung fibroblast cell strain (Flow 2002) grown in an homologous environment is investigated here. In sparse cultures, TGF‐β stimulates DNA synthesis over a broad concentration range (0.1‐10 ng/ml). Furthermore, it acts i