## Abstract Anti‐Fab antibody titers were positive in 70% of rheumatoid arthritis patients (54 of 77) and 3% (1 of 35) of healthy donors. Their specificity was examined by inhibition of the radioimmunoassay for anti‐Fab antibodies, which demonstrated that they are against the Fd region of the intac
✦ LIBER ✦
Secretion of anti–citrulline-containing peptide antibody by B lymphocytes in rheumatoid arthritis
✍ Scribed by Carelle C. Reparon-Schuijt; Wim J. E. van Esch; Cees van Kooten; Gerard A. Schellekens; Ben A. W. de Jong; Walther J. van Venrooij; Ferdinand C. Breedveld; Cornelis L. Verweij
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 106 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Recent data have shown that the most prominent and longest known genetic risk factors for rheumatoid arthritis (RA), HLA–DRB1 shared epitope alleles, are only associated with RA that is characterized by the presence of antibodies against cyclic citrullinated peptide (anti‐