𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Secondary Structure Peptide Mimetics: Design, Synthesis, and Evaluation of β-Strand Mimetic Thrombin Inhibitors

✍ Scribed by Boatman, P. Douglas; Ogbu, Cyprian O.; Eguchi, Masakatsu; Kim, Hwa-Ok; Nakanishi, Hiroshi; Cao, Bolong; Shea, J. Paul; Kahn, Michael


Book ID
111895125
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
211 KB
Volume
42
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


The design and synthesis of mimetics of
✍ Michael Kahn; Susanne Wilke; Barbara Chen; Kagari Fujita; Yu-Hwei Lee; Michael E 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB

The synthesis of an 11 membered ring bis-lactam, a system which is designed as a conformationally restricted mimetic of type I and type II beta-turns is described. Computer assisted molecular modeling was used to compare the predicted low energy conformers of the turn mimetic with idealized type I a

Design and synthesis of a bicyclic non-p
✍ Bruce L. Currie; John L. Krstenansky; Zhao-Lan Lin; Jiraporn Ungwitayatorn; Yu-H 📂 Article 📅 1993 🏛 Elsevier Science 🌐 French ⚖ 781 KB

hbrtmct: 9th~~ ~~~~~~'~~1 pvups of a biokgi~~ act& peptide can be mnqd on a non-pep&k framework in the "bkkgimlly act& wt,hnadon " it may be possible to maxrmiza the captor intrradios ad eliminate or r&a the mnbw of amide bonds that are atikbkfor pmteo&tk enzyme ckawtge. lhus, we han3 ~ig~~~~~~ the