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Secondary oxidation of cyclic 1,N2-propano and 1,N2-etheno-2′-deoxyguanosine DNA adducts. Consequences in oxidative stress biomarker development

✍ Scribed by Stéphane Barbati; Aurélie Bonnefoy; Alain Botta; Serge Chiron


Book ID
113531374
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
395 KB
Volume
80
Category
Article
ISSN
0045-6535

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✍ Magoichi Sako; Shinsuke Inagaki; Yukihiro Esaka; Yoshihiro Deyashiki 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 127 KB

The SO 4 --oxidation of cyclic 1,N 2 -propano-2%-deoxyguanosine, chemo-and regioselectively produced in the reaction of 2%-deoxyguanosine with excessive acetaldehyde or crotonaldehyde, resulted in the smooth formation of (4-hydroxy-5hydroxymethyltetrahydrofuran-2-ylimino)-(4-hydroxy-6-methyltetrahyd