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Secondary imatinib resistance associated with an aberrant bcr-abl fusion gene

✍ Scribed by Janssen, J J W M; Hochhaus, A; van Oostveen, J W; Waisfisz, Q; Schuurhuis, G J; Ossenkoppele, G J


Book ID
110055864
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
66 KB
Volume
18
Category
Article
ISSN
0887-6924

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Second case of CML with aberrant BCR-ABL
✍ Takeshi Sugimoto; Kentaro Ijima; Hisashi Hisatomi; Tohru Murayama; Ishikazu Mizu πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 81 KB

## Abstract We found a case of Ph‐positive chronic myelogenous leukemia (CML) patient with an atypical BCR‐ABL transcript that was undetectable by a routine reverse transcription polymerase chain reaction (RT‐PCR) for major BCR‐ABL. Additional RT‐PCR and sequence analyses have demonstrated that the