✦ LIBER ✦

Second primary cancers of endometrial carcinoma

✍ Scribed by Vitune Vongtama; Samuel S. Kurohara; Ahmed O. Badib; John H. Webster

Publisher: John Wiley and Sons
Year: 1970
Tongue: English
Weight: 325 KB
Volume: 26
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197010)26:4<842::aid-cncr2820260417>3.0.co;2-o

No coin nor oath required. For personal study only.

✦ Synopsis

Of 984 patients with corpus cancer treated at Roswell Park Memorial Institute (between 1940 and 1960), 116 (11.8%) were found to have second primaries; of these, 47 had breast cancer, 15 skin cancer, 27 other pelvic cancers, 15 abdominal cancer, 3 head and neck cancer, and 3 lymphoma or leukemia.

The incidence of second cancers increased with time and age, especially in the sixth and seventh decades. T h e risk of developing mammary cancer was found to be high within 5 years before the development of the uterine cancer. This time relationship is very interesting in that it supports the presumed association between corpus and breast cancer. T h e results of the present study also suggest that there is a subgroup of women who have abnormal estrogen stimulation of both the corpus and the breasts, leading to the development of both corpus and breast cancer.

ULTIPLE PRIMARY MALIGNANCIES WERE CON-M sidered rare and unusual when first described by Billroth4 in 1879. In recent years, not only has the number of reported cases increased, but also the frequency of occurrence of this phenomenon seems to have increased. T h e incidence of multiple primaries varies with different types of initial malignancies, with different sites of their origin, and the age of patients at the time of occurrence of each specific neoplasm.

T h e aim of this study was to determine the frequency distribution of second primaries associated with uterine cancers and to compare the incidence with those reported by other centers. The results indicate the high risk of occurrence of such cancers in these patients, particularly carcinoma of the breast.

Methods

During 1940 through 1960, 984 primary cases of histo!ogically proven endometrial car-

📜 SIMILAR VOLUMES

Second primary cancers in patients with

Second primary cancers in patients with lung carcinoma

✍ Fabio Levi; Lalao Randimbison; Van-Cong Te; Carlo La Vecchia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 66 KB 👁 1 views

There are only limited population-based data available regarding the risk of developing a second cancer after a diagnosis of lung carcinoma. ## METHODS. Data collected from the Cancer Registry of the Swiss Canton of Vaud (comprised of approximately 600,000 inhabitants) were used to estimate the i

Endometrial carcinoma in the cancer fami

Endometrial carcinoma in the cancer family syndrome

✍ T. Hakala; J.-P. Mecklin; M. Forss; H. Järvinen; P. Lehtovirta 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 408 KB 👁 1 views

Second primary tumors after prostate car

Second primary tumors after prostate carcinoma

✍ Fabio Levi; Lalao Randimbison; Van-Cong Te; Georges Erler; Carlo La Vecchia 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 65 KB 👁 1 views

Several large datasets have shown a reduced risk of all neoplasms after a diagnosis of prostate carcinoma but an increased incidence rate of urologic carcinoma has been suggested.

Second cancers following in situ carcino

Second cancers following in situ carcinoma of the breast

✍ Silvia Franceschi; Fabio Levi; Carlo La Vecchia; Lalao Randimbison; Van-Cong Te 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 69 KB 👁 2 views

Carcinoma in situ (CIS) of the breast has increased manyfold in incidence rates and as a proportion of new breast cancers following the introduction of mammographic breast screening. To provide population-based estimates of invasive breast cancer risk following CIS, we linked data on 249 incident pr

Pattern of second primary neoplasms foll

Pattern of second primary neoplasms following breast cancer

✍ Parikh, Bhavna; Advani, Suresh 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB 👁 2 views

Background: Second primary neoplasms (SPN) have been seen with diseases such as breast cancer and Hodgkin's disease. Therapeutic agents used for their treatment have been found responsible for the development of SPN in some cases. In addition, genetic factors are known to contribute to their develop

Survival of first and second primary bre

Survival of first and second primary breast cancer

✍ Eliezer Robinson; Gad Rennert; Hedy S. Rennert; Alfred I. Neugut 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB 👁 2 views