Second-harmonic generation optical activity of a polypeptide α-helix at the air∕water interface
✍ Scribed by Mitchell, S. A.; McAloney, R. A.; Moffatt, D.; Mora-Diez, N.; Zgierski, M. Z.
- Book ID
- 120193621
- Publisher
- American Institute of Physics
- Year
- 2005
- Tongue
- English
- Weight
- 466 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0021-9606
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We have used second harmonic generation to directly observe chemical changes in a lipid monolayer. We observed that pK, of phexadecyl aniline at the air/water interface is 3.6& 0.2 versus 5.3 fO.l in the bulk. This fiftyfold increase in acidity is due to the higher free energy of a charged species a
Monolayers of two nitroaniline-terminated amphiphilic compounds that differ from each other only by a methylene group in the hydrocarbon chain arestudied at the air-water interface by optical second harmonic generation and ellipsometry. The nitroanilino groups exhibit significantly different orderin