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Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): A better mousetrap? A review of the clinical evidence

✍ Scribed by Sai-Hong Ignatius Ou


Book ID
119222876
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
556 KB
Volume
83
Category
Article
ISSN
1040-8428

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## Abstract A range of target‐based agents for the treatment of solid tumors are in development. The epidermal growth factor receptor (EGFR) has been identified as a relevant target as it is involved in regulating several cellular functions important in the proliferation and survival of cancer cell