Searching for genes influencing a complex disease: the case of coeliac disease
✍ Scribed by Naluai, Åsa Torinsson; Ascher, Henry; Nilsson, Staffan; Wahlström, Jan
- Book ID
- 110027218
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 204 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1018-4813
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Although coeliac disease (CD) is strongly associated with the HLA alleles B8 and DR3, the genetic basis of this illness remains obscure. Recent studies show that at least two unlinked loci are involved. Most studies agree on recessivity at the HLAunlinked locus but differ with respect to dominance o