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Search for linkage to schizophrenia on the X and Y chromosomes

✍ Scribed by DeLisi, Lynn E. ;Devoto, Marcella ;Lofthouse, Raymond ;Poulter, Mark ;Smith, Angela ;Shields, Gail ;Bass, Nick ;Chen, Gang ;Vita, Antonio ;Morganti, Carla ;Ott, Jurg ;Crow, Timothy J.

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
848 KB
Volume
54
Category
Article
ISSN
0148-7299

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DeLisi et al. (199413) have examined the X and Y chromosomes for linkage to schizophrenia in 126 small families and report a small positive LOD score for the marker DXS7, adjacent to the MA0 locus at Xp11.4-11.3. Because of this, we have examined the DXS7 for linkage to schizophrenia using 17 pedig

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The hypothesis that psychosis arises as a part of the genetic diversity associated with the evolution of language generates the prediction that illness will be linked to a gene determining cerebral asymmetry, which, from the evidence of sex chromosome aneuploidies, is present in homologous form on t