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Screening Petrochemicals for Contact Hypersensitivity Potential: A Comparison of the Murine Local Lymph Node Assay with Guinea Pig and Human Test Data

✍ Scribed by D.A. Edwards; T.M. Soranno; M.A. Amoruso; R.V. House; A.C. Tummey; G.W. Trimmer; P.T. Thomas; P.L. Ribeiro


Book ID
115608350
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
458 KB
Volume
23
Category
Article
ISSN
0272-0590

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A murine local lymph node assay has been developed for the identification of contact sensitizing chemicals. In the present study, the performance of the local lymph node assay has been evaluated with twenty-four coded chemicals of previously unknown skin sensitizing potential and the results compar