Quantitative comparison of the results obtained by the multiple-dose guinea pig maximization test and the non-radioactive murine local lymph-node assay for various biocides

Skin sensitization potency of isoeugenol

Skin sensitization potency of isoeugenol and its dimers evaluated by a non-radioisotopic modification of the local lymph node assay and guinea pig maximization test

✍ Masahiro Takeyoshi; Kenji Iida; Keiko Suzuki; Shunsuke Yamazaki 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB

## Abstract Allergic contact dermatitis is the serious unwanted effect arising from the use of consumer products such as cosmetics. Isoeugenol is a fragrance chemical with spicy, carnation‐like scent, is used in many kinds of cosmetics and is a well‐known moderate human sensitizer. It was previousl