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Screening of lung cancer samples using gene expression profiling

✍ Scribed by Wolfl, Stefan; Odyvanova, Larissa; Kroll, Torsten; Sanger, Jorg; Clement, Joachim

Book ID
109831528
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
31 KB
Volume
27
Category
Article
ISSN
1061-4036

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Lung cancer is a highly aggressive neoplasm with 85% mortality. To identify new tumor-associated genes, we compared the expression profile of a primary metastasizing adenocarcinoma with normal airway epithelial cells. Two cDNA libraries of up-and downregulated genes were generated, comprising 253 an