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Screening of Interleukin-2 Production Inhibitor with Mouse Thymoma EL4 Cells.

โœ Scribed by Soon Cheol Ahn; Bo Yeon Kim; Won Keun Oh; Dae Ook Kang; Gun Young Heo; Min Soo Kim; Myung Sun Lee; Jong Seog Ahn

Publisher
John Wiley and Sons
Year
2003
Weight
74 KB
Volume
34
Category
Article
ISSN
0931-7597

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EL 4-6.1 cells, variants of the murine EL4 thymoma cell line, can be activated by interleukin 1 (IL-I 1 or phorbol 12-myristdte-13-dcetate (PMA), or PMA + IL-I to secrete interleukin 2 (IL-2) and interleukin 4 (IL-4) and to express the IL-2 receptor (IL-2R). To compare the different activation pathw