Discovery of high-affinity peptide ligan
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Nianhuan Yao; Chun-Yi Wu; Wenwu Xiao; Kit S. Lam
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Article
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2008
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Wiley (John Wiley & Sons)
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English
β 255 KB
## Abstract Vancomycin, an important antibiotic against medically relevant gramβpositive bacteria such as methicillinβresistant __Staphylococcus aureus__, exerts its antibacterial effects by binding with moderate affinity to the Cβterminal LysβDβAlaβDβAla motif (Kaa) of the bacterial cell wall pept