To assess the value of inhibin A as an additional second-trimester maternal serum marker of Down's syndrome we studied 56 affected and 280 unaffected pregnancies matched for gestational age. The median level in the cases was 1.62 multiples of the gestation-specific median (MOM) in the controls, with
Screening for Down's syndrome in early and late first and second trimester using six maternal serum markers
✍ Scribed by M Christiansen; SO Larsen; C Oxvig; Q-P Qin; JM Wagner; MT Overgaard; GJ Gleich; L Sottrup-Jensen; B Nørgaard-Pedersen
- Book ID
- 110723433
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 113 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0009-9163
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The potential of the maternal serum concentration of schwangerschaftsprotein 1 (MSSP1) as a marker for Down syndrome (DS) pregnancies was evaluated in the fifth to the 20th gestational week using 156 DS pregnancies and 546 unaffected control pregnancies. In DS pregnancies, the median of the multiple
Second-trimester maternal serum screening for fetal Down's syndrome is well established in many Western countries. Its usefulness and acceptability is unknown in the Asian countries. Between June 1994 and December 1996, we offered second-trimester serum AFP and hCG screening to pregnant women in Hon