Sc(OTf)3-catalyzed diastereoselective synthesis of 3,4-dihydro-4-amino-2H-1-benzopyrans
โ Scribed by J.S Yadav; B.V.Subba Reddy; K.Chandra Sekhar; V Geetha
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 73 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Highly enantioselective reduction of 3,4-dihydro-2,2-dimethyl-2H-l-benzopyran-4-ones 3 s-e by BH3 was achieved in the presence of catalytic amounts of Corey's oxazaborolidine 4 to afford the corresponding 3,4-dihydro-2,2dimetbyl-2H-l-~nzopyran-4-ols 2a-e in quantitative yields. These benzopyran-4-ol
Glycals react smoothly with o-hydroxybenzaldehydes and trimethyl orthoformate in the presence of a catalytic amount of scandium triflate under mild reaction conditions to afford the corresponding cis-annelated pyranobenzopyrans in good yields with high diastereoselectivity.