✦ LIBER ✦

Scoliosis and lung function in spinal muscular atrophy

✍ Scribed by D. Robinson; C. S. B. Galasko; C. Delaney; J. B. Williamson; J. L. Barrie

Publisher: Springer
Year: 1995
Tongue: English
Weight: 630 KB
Volume: 4
Category: Article
ISSN: 0940-6719
DOI: 10.1007/bf00301032

No coin nor oath required. For personal study only.

✦ Synopsis

The notes and radiographs of 43 patients with a confirmed diagnosis of spinal muscular atrophy were reviewed. A significant inverse linear relationship between the severity of scoliosis and the percentage of predicted vital capacity and peak flow was found. The patients who stood had a significantly better lung function than patients who were confined to a wheelchair, and their scoliosis deteriorated significantly more slowly. Sixteen patients underwent surgical spinal stabilisation, 4 with Harrington instrumentation and 12 with segmental spinal instrumentation, at an average age of 12 years and 11 months. The average curve correction achieved was 40%. The decline in lung function seen pre-operatively was not only reversed, but a significant improvement was found at final follow-up.

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