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Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling

โœ Scribed by Ratcliffe, Kirsty E; Tao, Qi; Yavuz, Burju; Stoletov, Konstantin V; Spring, Simone C; Terman, Bruce I


Book ID
110066938
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
368 KB
Volume
21
Category
Article
ISSN
0950-9232

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t