Schwann-like cells seeded in acellular nerve grafts improve nerve regeneration
β Scribed by Fan, Lihong; Yu, Zefeng; Li, Jia; Dang, Xiaoqian; Wang, Kunzheng
- Book ID
- 125399700
- Publisher
- BioMed Central
- Year
- 2014
- Tongue
- English
- Weight
- 818 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1471-2474
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π SIMILAR VOLUMES
The bridging of nerve gaps is still one of the major problems in peripheral nerve surgery. The present experiment describes our attempt to engineer different biologic nerve grafts in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into 2-cm autologous acellular nerve grafts
## Abstract Previous studies have demonstrated the potential of growth factors in peripheral nerve regeneration. A method was developed for sustained delivery of nerve growth factor (NGF) for nerve repair with acellular nerve grafts to augment peripheral nerve regeneration. NGFβcontaining polymeric