Peripheral nerve regeneration through nerve guides seeded with adult Schwann cells
✍ Scribed by A.D. Ansselin; T. Fink; D.F. Davey
- Book ID
- 110852223
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 826 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0305-1846
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📜 SIMILAR VOLUMES
## Abstract We assessed the effects of FK506 administration on regeneration after a 6‐mm gap repair with a collagen guide seeded with allogeneic Schwann cells (SCs) in the mouse sciatic nerve. SCs were isolated from predegenerated adult sciatic nerves and expanded in culture using a defined medium,
The peripheral nervous system retains a considerable capacity for regeneration. However, functional recovery rarely returns to the preinjury level no matter how accurate the nerve repair is, and the more proximal the injury the worse the recovery. Among a variety of approaches being used to enhance