Schiff-base Amino Alcohol-zinc Complex for Enantioselective Addition of Phenylacetylene to Aromatic Ketones
β Scribed by CHEN, C; HONG, L; WANG, Q; ZHANG, B; WANG, R
- Book ID
- 123500362
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 502 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1005-9040
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π SIMILAR VOLUMES
## Abstract (__S__)β(1βBenzylpyrrolidinβ2βyl)diphenylmethanol and cinchonine were evaluated as promotors in the asymmetric additions of phenylacetylene to ketones, in order to prepare chiral propargylic alcohols. Good yields (up to 89%) and moderate enantioselectivities (up to 77.9% __ee__) were ac
## Abstract The easily prepared and recoverable chiral __N__βsulfonylated __Ξ²__βamino alcohol **2** in combination with Ti(OPrβ__i__)~4~was found to be an effective chiral catalyst for the enantioselective addition of alkynylzinc to ketones, which gave the useful products, __i.e.__ chiral tertiary