Schedule-dependent cytotoxicity of 5-fluorouracil and irinotecan in a colon cancer cell line
β Scribed by Yasuhiro Inoue; Chikao Miki; Hideki Watanabe; Junichiro Hiro; Yuji Toiyama; Eiki Ojima; Hidenori Yanagi; Masato Kusunoki
- Book ID
- 106180026
- Publisher
- Springer Japan
- Year
- 2007
- Tongue
- English
- Weight
- 341 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0944-1174
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Because of conflicting reports of clinical synergy, we used the tetrazolium-based colorimetric (MTT) assay to test in vitro combination effects of methotrexate (MTX) plus 5fluorouracil (FUra) in 4 schedules on 2 human non-small-cell lung cancer cell lines (adenocarcinoma, NCLH23; bronchioalveolar-ce
## Abstract The mode of action of the combination treatment 5βfluorouracil (5βFU) and levamisole in colorectal cancer patients is unknown. It is postulated that the beneficial effect may be explained by an immunomodulatory effect on Kupffer cell (KC) cytotoxicity. We evaluated the effect of levamis