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Scandium triflate catalyzed diazocarbonyl insertions into heteroatomhydrogen bonds

✍ Scribed by Sunil V. Pansare; Rajendra P. Jain; Annyt Bhattacharyya

Book ID
104261778
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
260 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

Scandium triflate is an efficient catalyst for diazocarbonyl insertion reactions into O-H, S-H and carbamate N-H bonds. The O-H and S-H insertion reactions proceed at ambient temperature and selective O-H insertion is possible in the presence of a earbamate N-H. A novel approach to a-amino acids involving intrarnolecular earbene/N-H insertion as the key step has been demonstrated.

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