Scale-up of hydrophobic interaction chromatography for purification of SN-07 was studied. The height equivalent to a theoretical plate of the adsorbent gel (Sepaheads FP-PH 12) was kept constant for various superficial liquid velocities and column diameters. The efficiency of purification was also c
β¦ LIBER β¦
Scale-up of hydrophobic interaction chromatography for the purification of a DNA vaccine against rabies
β Scribed by M.M. Diogo; S. Ribeiro; J.A. Queiroz; G.A. Monteiro; P. Perrin; N. Tordo; D.M.F. Prazeres
- Book ID
- 110227971
- Publisher
- Springer Netherlands
- Year
- 2000
- Tongue
- English
- Weight
- 44 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0141-5492
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## Abstract The behavior of a series of pure proteins partitioned in aqueous twoβphase systems is compared with their behavior during mild hydrophobic interaction chromatography (HIC). A simple theoretical rationale for this comparison is presented based upon solvophobic theory. Similarities were f