We describe the stereoselective synthesis of (2'S)-2'-deoxy-2'-C-methyladenosine ( ) and (2'S)-2'-deoxy-2'-C-methylinosine ( ) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-O-(2,6dichlorophenyl)inosine as starting material. The methyl group at the 2'-position was introd
✦ LIBER ✦
Scalable and Efficient Synthesis of 2′-Deoxy-2′-N-phthaloyl Nucleoside Phosphoramidites for Oligonucleotide Synthesis.
✍ Scribed by Alexander Karpeisky; David Sweedler; Peter Haeberli; Javier Read; Keith Jarvis; Leonid Beigelman
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 215 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
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