𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Scalable and Efficient Synthesis of 2′-Deoxy-2′-N-phthaloyl Nucleoside Phosphoramidites for Oligonucleotide Synthesis.

✍ Scribed by Alexander Karpeisky; David Sweedler; Peter Haeberli; Javier Read; Keith Jarvis; Leonid Beigelman


Publisher
John Wiley and Sons
Year
2003
Weight
215 KB
Volume
34
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


📜 SIMILAR VOLUMES


Synthesis of (2′S)-2′-Deoxy-2′-C-methylp
✍ Gerardo Caballero; Mariana Gallo; Javier M. Montserrat; Adolfo M. Iribarren 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 154 KB 👁 1 views

We describe the stereoselective synthesis of (2'S)-2'-deoxy-2'-C-methyladenosine ( ) and (2'S)-2'-deoxy-2'-C-methylinosine ( ) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-O-(2,6dichlorophenyl)inosine as starting material. The methyl group at the 2'-position was introd

Synthesis of (2′S)- and (2′R)-2′-Deoxy-2
✍ Timofei S. Zatsepin; Yulia M. Ivanova; Tatiana S. Oretskaya 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 1 views

## Abstract Syntheses of specified 2′‐modified nucleosides were achieved: __a__) __via__ oximation of the 5′,3′‐blocked 2′‐oxocytidine, followed by reduction, or __b__) by intramolecular nucleophilic addition of 3′‐(2‐methoxyethoxy)carbamate to the 2′‐position with opening of __O__^2^,2′‐anhydrouri