Determination of DNA single-strand break
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Einhaus, M. ;Holz, O. ;Mei�ner, R. ;Krause, T. ;Warncke, K. ;Held, I. ;Scherer,
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Article
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1994
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Springer-Verlag
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English
⚖ 636 KB
The detection of DNA single-strand breaks (SSB) in human mononucleated white blood cells (MWBC) using a modified version of the nick translation assay is presented. This assay allows rapid and sensitive examination of SSB using only 5 ml heparinized blood fo'~ an eightfold determination. The assay w