Saturable first-pass metabolism of sulfisoxazole n1-acetyl in rats
β Scribed by Duane C. Bloedow; William L. Hayton
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 455 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
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## Abstract The contribution of gastrointestinal tract (GIT), liver, and lung towards the firstβpass metabolism of acetaminophen was examined using 3βweekβold, 10βweekβold and 1βyearβold rats after administration of 30mgkg^β1^ doses by intraβarterial, intravenous, intraperitoneal, and oral routes.
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