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Sarcolemmal Na+-Ca2+exchange and Ca2+-pump activities in cardiomyopathies due to intracellular Ca2+-overload

✍ Scribed by Naranjan S. Dhalla; Vincenzo Panagia; Naoki Makino; Robert E. Beamish

Publisher: Springer
Year: 1988
Tongue: English
Weight: 383 KB
Volume: 82
Category: Article
ISSN: 0300-8177
DOI: 10.1007/bf00242519

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## Abstract Multiple Ca^2+^ entry routes have been implicated in excitotoxic Ca^2+^ loading in neurons and reverse‐operation of sodium–calcium exchangers (NCX) has been shown to contribute under conditions where intracellular Na^+^ levels are enhanced. We have investigated effects of KB‐R7943, an i