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Alterations in heart sarcolemmal Ca2+-ATPase and Ca2+-binding activities due to oxygen free radicals

โœ Scribed by M. Kaneko; P. K. Singal; N. S. Dhalla


Publisher
Springer
Year
1990
Tongue
English
Weight
571 KB
Volume
85
Category
Article
ISSN
0300-8428

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Although in vitro studies have shown that oxygen free radicals depress the sarcolemmal Ca(2+)-pump activity and thereby may cause the occurrence of intracellular Ca2+ overload for the genesis of contractile failure, the exact relationship between changes in sarcolemmal Ca(2+)-pump activity and cardi