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Sar1-p-Benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor

✍ Scribed by R. Bossé; G. Servant; L.-M. Zhou; G. Boulay; G. Guillemette; E. Escher

Book ID
119118000
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
649 KB
Volume
44
Category
Article
ISSN
0167-0115

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✍ Michel Bernier; Emannuel Escher 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 German ⚖ 219 KB 👁 1 views

## Abstract The synthesis of [Sar^1^, Val^5^, (4′‐azido‐3′,5′‐ditritio)Phe^8^] angiotensin II from a iodinated precursor peptide is described. The principal problems of this synthesis and their resolution are discussed: (i) The β‐induced autophotolysis of the highly tritiated (73 Ci/mmol) and photo