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Sansalvamide: A new cytotoxic cyclic depsipeptide produced by a marine fungus of the genus Fusarium

โœ Scribed by Gilbert N Belofsky; Paul R Jensen; William Fenical

Book ID
104261187
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
250 KB
Volume
40
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

A new cyclic pentadepsipeptide, sansalvamide (1), has been isolated from organic extracts of the mycelium of a fungus of the genus Fusarium collected from the surface of the seagrass Halodule wrightii. The structure of 1 was determined through extensive analysis of 1D and 2D NMR data. Sansalvamide exhibited selective in vitro cytotoxicity toward COLO 205 colon and SK-MEL-2

๐Ÿ“œ SIMILAR VOLUMES

Exumolides A and B: Antimicroalgal cycli
Exumolides A and B: Antimicroalgal cyclic depsipeptides produced by a marine fungus of the genus Scytalidium
โœ Kelly M. Jenkins; Matthew K. Renner; Paul R. Jensen; William Fenical ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 259 KB

Two new cyclic hexadepsipeptides, exumolides A (1) and B (2) were produced by a marine fungus, identified as a Scytalidium sp., collected in the Bahamas. Two dimensional NMR methods, coupled with tandem mass spectrometry (MS-MS), were used to establish the structures of the new compounds. The exumol