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Exumolides A and B: Antimicroalgal cyclic depsipeptides produced by a marine fungus of the genus Scytalidium

โœ Scribed by Kelly M. Jenkins; Matthew K. Renner; Paul R. Jensen; William Fenical

Book ID
104259024
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
259 KB
Volume
39
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Two new cyclic hexadepsipeptides, exumolides A (1) and B (2) were produced by a marine fungus, identified as a Scytalidium sp., collected in the Bahamas. Two dimensional NMR methods, coupled with tandem mass spectrometry (MS-MS), were used to establish the structures of the new compounds. The exumolides exhibit antimicroalgal activity against the unicellular chlorophyte Dunaliella sp. at 20 lag ml "l in liquid media cell growth assays.

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โœ Gilbert N Belofsky; Paul R Jensen; William Fenical ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 250 KB

A new cyclic pentadepsipeptide, sansalvamide (1), has been isolated from organic extracts of the mycelium of a fungus of the genus Fusarium collected from the surface of the seagrass Halodule wrightii. The structure of 1 was determined through extensive analysis of 1D and 2D NMR data. Sansalvamide e