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Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues

✍ Scribed by Zdenek Dvorak; Martin Modriansky; Vilim Simanek; Jitka Ulrichova; Jaroslav Vicar; Jiri Vrba; Daniela Walterova

Book ID
119378156
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
41 KB
Volume
158
Category
Article
ISSN
0378-4274

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Polycyclic hydrocarbon activation and me
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## Abstract The metabolism of benz(a)anthracene (BA), 7,12‐di‐methylbenz(a)anthracene (DMBA) and benzo(a)pyrene (BP) by human mammary epithelial cell aggregates in culture has been investigated using non‐neoplastic tissues obtained from eight patients undergoing reduction mammoplasty. All three hyd