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Sanguinarine activates polycyclic aromatic hydrocarbon associated metabolic pathways in human oral keratinocytes and tissues

✍ Scribed by Jeffrey M. Karp; Kapila A. Rodrigo; Ping Pei; Matthew D. Pavlick; Jeffrey D. Andersen; Dennis J. McTigue; Henry W. Fields; Susan R. Mallery

Book ID
119378113
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
126 KB
Volume
158
Category
Article
ISSN
0378-4274

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## Abstract The metabolism of benz(a)anthracene (BA), 7,12‐di‐methylbenz(a)anthracene (DMBA) and benzo(a)pyrene (BP) by human mammary epithelial cell aggregates in culture has been investigated using non‐neoplastic tissues obtained from eight patients undergoing reduction mammoplasty. All three hyd