## Abstract The expression of the mouse mammary tumor virus (MMTV) in hormoneโinduced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinityโ and ionโexchange chromatography columns. The purified viral
Sandwich enzyme immunoassay of mouse mammary tumor virus
โ Scribed by M. Takahashi; S. Saga; S. Nagayoshi; M. Imai; Y. Tsutsui; K. Kato; M. Hoshino
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 243 KB
- Volume
- 37
- Category
- Article
- ISSN
- 1420-682X
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## Abstract Mouse mammary tumor virus (MMTV) is a hormonally regulated, oncogenic virus of mice. MMTVโlike virus DNA has previously been detected in human breast cancers, liver disease, and liver cancers. It is hypothesized that local hormonal effects might be of primary importance in determining M
## Abstract A radioimmunoassay for the antigens of the mouse mammary tumour virus has been developed. ^125^Iodineโlabelling of intact virus [derived from mammary tumours of (C3H ร 020) F1 mice] followed by ether extraction and separation of the ether and water layers resulted in a separation of the