## Abstract The expression of the mouse mammary tumor virus (MMTV) in hormoneโinduced mammary tumors was investigated by means of a radioimmunoassay for two major MMTV proteins, gp52 and p27. MMTV proteins were isolated on lectin affinityโ and ionโexchange chromatography columns. The purified viral
Identification of human homologues of the mouse mammary tumor virus receptor
โ Scribed by A. F. R. Stewart
- Publisher
- Springer Vienna
- Year
- 2002
- Tongue
- English
- Weight
- 60 KB
- Volume
- 147
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The mouse mammary tumor virus enters mammary epithelial cells via a plasma membrane protein that binds to a viral envelope glycoprotein, gp52. In intact cells, this gp52 receptor can be phosphorylated by activators of protein kinase A and protein kinase C (PKC), but this modification does not occur
## Abstract Mouse mammary tumor virus (MMTV) is a hormonally regulated, oncogenic virus of mice. MMTVโlike virus DNA has previously been detected in human breast cancers, liver disease, and liver cancers. It is hypothesized that local hormonal effects might be of primary importance in determining M
## Abstract Gene silencing by aberrant epigenetic chromatin alteration is a wellโrecognized event contributing to tumorigenesis. Although genetically engineered tumorโprone mouse models have proven a powerful tool in understanding many aspects of carcinogenesis, to date few studies have focused on