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Sample size for sequentially monitored trials with noncompliance and lag

โœ Scribed by Edward Lakatos

Book ID
113297265
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
77 KB
Volume
12
Category
Article
ISSN
0197-2456

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## Abstract In a randomized clinical trial (RCT), noncompliance with an assigned treatment can occur due to serious side effects, while missing outcomes on patients may happen due to patients' withdrawal or loss to follow up. To avoid the possible loss of power to detect a given risk difference (RD