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Sample size determination for clinical trials with co-primary outcomes: exponential event times

✍ Scribed by Hamasaki, Toshimitsu; Sugimoto, Tomoyuki; Evans, Scott; Sozu, Takashi

Book ID
118766723
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
226 KB
Volume
12
Category
Article
ISSN
1539-1604

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Estimation of sample size in clinical trials requires knowledge of parameters that involve the treatment effect and variability, which are usually uncertain to medical researchers. The recent release within the European Union of a Note for Guidance from the Commission for Proprietary Medical Product