Samarium(II) iodide promoted radical ring opening reactions of cyclopropyl ketones
β Scribed by Robert A. Batey; William B. Motherwell
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 269 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Functionalized cyclopropyl ketones have been found to undergo facile reductive cyclopropane ring opening with samarium (II) diiodide in the presence of a proton source. These reactions were exceedingly rapid, taking place in most cases at -78Β°C under neutral conditions. An ester group substitut
Radical ring-opening reactions of bicyclo[4.2.0]octanones, its C6 alkyl derivatives, and tricyclic ketones promoted by SmI 2 gave cyclohexanones via fission of the external cyclobutane bond. The CO 2 Me, CN, and phenyl derivatives led to the production of the eight-membered ring compounds through cl
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