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Samarium diiodide-mediated synthesis of D-3,4,5,6-tetra-O-benzyl-myo-inositol

✍ Scribed by J.P. Guidot; T. Le Gall; C. Mioskowski


Book ID
104214682
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
137 KB
Volume
35
Category
Article
ISSN
0040-4039

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The synthesis of the optically pure 1,4,5,6-tetra-O-benzyl-myo-inositols was achieved in four steps via diastereomeric 2,3-spire-acetals of myo-inositol with Land D-camphor as the key intermediates. Camphor dimethyl acetal was used for the acetalation reaction. The diastereomers were benzylated and