Salvage chemotherapy in relapsed germ cell tumors
β Scribed by J. Beyer; O. Rick; W. Siegert; C. Bokemeyer
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 76 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0724-4983
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During the past 10 years, high-dose chemotherapy (HDCT) has emerged as a feasible and curative treatment option for patients with multiply relapsed and/or refractory germ-cell tumors. Increasing experience and the results from clincial trials have helped to optimize the application of HDCT and to de
## Background: Only 20-30% of patients with refractory or recurrent germ cell tumors (gct) are cured by salvage chemotherapy. irinotecan, a new derivative of camptothecin, is a potent anticancer agent against a variety of solid cancers. the current pilot study investigated the efficacy of salvage c