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Salt intake sensitization and gene expression of the hypothalamic renin–angiotensin system

✍ Scribed by D.T.B. Pereira-Derderian; S. Chiavegatto; J.V. Menani; L.A. De LUCA Jr.

Book ID
116241971
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
64 KB
Volume
54
Category
Article
ISSN
0195-6663

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When an ∼30 centiMorgan (cM) region of chromosome 13 containing the renin gene from the Dahl salt‐resistant rat (R) was introgressed into the Dahl salt‐sensitive rat (S), the resulting congenic rat (designated S.R__‐Ren__) had a systolic blood pressure on a 2% (w/w) salt diet that was 24 mmHg lower