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Effects of omapatrilat on the renin-angiotensin system in salt-sensitive hypertension

✍ Scribed by Carlos M. Ferrario; Ronald D. Smith; Bridget Brosnihan; Mark C. Chappell; Vito M. Campese; Ole Vesterqvist; Wei-chi Liao; Michael C. Ruddy; Clarence E. Grim

Book ID
117600838
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
149 KB
Volume
15
Category
Article
ISSN
0895-7061

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When an ∼30 centiMorgan (cM) region of chromosome 13 containing the renin gene from the Dahl salt‐resistant rat (R) was introgressed into the Dahl salt‐sensitive rat (S), the resulting congenic rat (designated S.R__‐Ren__) had a systolic blood pressure on a 2% (w/w) salt diet that was 24 mmHg lower