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Control of vascular changes by renin–angiotensin–aldosterone system in salt-sensitive hypertension

✍ Scribed by Zhao-hua Zeng; Bi-hui Luo; Yu-jing Gao; Cheng-jian Su; Chao-chu He; Jia-ji Yi; Nina Li; Robert M.K.W. Lee


Book ID
113585050
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
109 KB
Volume
503
Category
Article
ISSN
0014-2999

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When an ∼30 centiMorgan (cM) region of chromosome 13 containing the renin gene from the Dahl salt‐resistant rat (R) was introgressed into the Dahl salt‐sensitive rat (S), the resulting congenic rat (designated S.R__‐Ren__) had a systolic blood pressure on a 2% (w/w) salt diet that was 24 mmHg lower