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Salt Bridges Stabilize the Folded Structure of Barnase

✍ Scribed by Vijayakumar, M.; Zhou, Huan-Xiang

Book ID
126903892
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
87 KB
Volume
105
Category
Article
ISSN
0022-3654

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## Abstract We present a study of the role of salt bridges in stabilizing a simplified tertiary structural motif, the coiled‐coil. Changes in GCN4 sequence have been engineered that introduce trial patterns of single and multiple salt bridges at solvent exposed sites. At the same sites, a set of al